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Cholyl-l-lysyl-fluorescein

WebFeb 1, 2024 · The fluorescent bile acid-derivative cholyl-l-lysyl-fluorescein (CLF) was used to quantify drug-induced efflux transport inhibition in hepatocytes. … WebApr 24, 2024 · Cholyl-lysyl-fluorescein (CLF) is a synthetic bile acid analog similar to cholyl glycine, and is taken up by hepatocytes in the liver and excreted into bile …

Determining functional activity of MRP2 and/or MRP3 efflux …

WebAbstract: Background: Cholyl-lysyl-fluorescein (CLF) is a fluorescein-labelled bile acid whose biological behaviour closely resembles that of naturally occurring cholyl glycine. … WebApr 1, 2010 · Cholyl-L-lysyl-fluorescein (CLF) is a fluorescent bile salt derivative that is being developed as an agent for determining in vivo liver function. However, the … drakorku squid game https://smallvilletravel.com

Maintenance of Primary Hepatocyte Functions - ScienceDirect

WebQuantum yield. 0.79001, 0.952. CLF is a fluorescein-labeled bile acid analog that closely parallels the cellular binding and uptake properties of cholic acid derivatives. It is a divalent 'unipolar' anionic fluorescent monohydroxy bile salt analog with physical, biological and … WebDirk de Waart is an academic researcher. The author has contributed to research in topic(s): Bile acid. The author has an hindex of 1, co-authored 2 publication(s) receiving 3 citation(s). WebCorning® Cholyl-Lysyl-Fluorescein (CLF), 1 mg Corning® Cholyl-Lysyl-Fluorescein (CLF), 1 mg by Corning Life Sciences Manufacturer Corning Life Sciences Model: … drakor list romance

Quantification of Drug-Induced Inhibition of Canalicular …

Category:(PDF) Cholyllysyl fluroscein and related lysyl fluorescein …

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Cholyl-l-lysyl-fluorescein

High-Fidelity Drug-Induced Liver Injury Screen Using

WebDec 3, 2024 · By incubation with cholyl-l-lysyl-fluorescein (CLF), a fluorescent bile salt derivative that can be taken up by hepatocytes and effluxed into bile canaliculi through ATP-binding cassette subfamily C member 2 (ABCC2, also known as multidrug resistance-associated protein 2) (de Waart et al., 2010), LBDXL 3W hepatocytes demonstrated … WebOct 20, 2024 · Cholyl- l -lysyl-fluorescein (CLF) was purchased from BD Biosciences. Pitavastatin was obtained from LKT Laboratories. Other statins and bosentan were …

Cholyl-l-lysyl-fluorescein

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WebCholyl-L-lysyl-fluorescein (CLF) is a fluorescent bile salt derivative that is being developed as an agent for determining in vivo liver function. However, the mechanisms of uptake and excretion... Web开馆时间:周一至周日7:00-22:30 周五 7:00-12:00; 我的图书馆

WebSep 1, 2015 · Recently, imaging of biliary excretion of the fluorescent probe cholyl-L-lysyl-fluorescein (CLF) from rat hepatocytes was proposed to quantify drug-induced efflux transport inhibition (Barber et ... WebJun 29, 2024 · CuSNPs also introduced hepatocyte spheroid injury through alteration of mitochondrial membrane potential and reactive oxygen species, that could be reversed by N-acetyl- l -cysteine. CuSNPs significantly decreased the activity of BSEP transporter by downregulating its mRNA and protein levels. Activity of the MRP2 transporter remained …

WebWith reference to Figure 32, Cholyl-L-Lysyl-Fluorescein (CLF) is a fluorescein-labelled bile acid whose biological behaviour closely resembles cholyl glycine, and is taken up by the OATP1B3... WebProduct Name: Cholyl-L-Lysyl-Fluorescein (CLF) Catalog number: 33288 Supplier: Medical Isotopes, Inc. 100 Bridge Street Pelham, NH 03076 USA Tel: +1-603-635-2255 …

WebCholyl-lysyl-fluorescein C51H63N3O11S CID 56626462 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological …

Webdrug hepatotoxicity, cholyl-l-lysyl-fluorescein, hepatobiliary transporters, DILI Bile flow is an essential biological process that facilitates the elimination of many drugs … drakor lamaWebCholyl-L-lysyl-fluorescein (CLF) is a fluorescent bile salt derivative that is being developed as an agent for determining in vivo liver function. However, the … drakor l.u.c.a. season 2WebCholyl-lys-fluorescein (CLF/cholyl-lys-F) is a bile acid (BA) analog, developed to investigate and determine in vivo liver functions. The compound is actually a fluorescein … radmila juračkováWebDec 3, 2024 · Cells that attached and spread on a rigid surface, such as a Petri dish, encountered mechanical stress and typically assembled actin filaments associated with myosin to form contractile stress fibers for force-balance between the cell and its … radmila karaklajic biografijaWebCholyl L Lysyl Fluorescein, supplied by Corning Life Sciences, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article … drakor live up to your nameWebMar 28, 2024 · The rhodamine 123 transport assay and active collection of cholyl-lysyl-fluorescein exhibited the specific functions of bile secretion and transportation at day 14 compared to those in monolayer ... drakorluvWebThe rhodamine 123 transport assay and active collection of cholyl-lysyl-fluorescein exhibited the specific functions of bile secretion and transportation at day 14 compared to those in monolayer and hydrogel culture systems. The metabolomics analysis with 1075 peak pairs showed that serotonin, as a key molecule of the tryptophan metabolism ... radmila jurackova brno