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Auto-fatty acylation of transcription factor RFX3 regulates …
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RFX3, RFX4, and RFX7 have been reported to have relatively high expression in human fetal cortex.23 To determine whether specific cell types are affected by RFX haploinsufficiency, we examined single-cell transcriptomes from developing and adult human cortex (Fig. 3a–f, Figure S3A, B).11,24 In developing human … See more We identified and obtained clinical information from 18 individuals bearing loss-of-function variants in RFX3 via GeneMatcher.17 Genotypic information is provided in Table 1, clinical phenotypes are summarized in … See more Dysregulated gene expression, especially in upper-layer cortical neurons, has been implicated in ASD pathogenesis.11,26 Given the expression of RFX3 in layer 2/3 neurons and the autistic features of individuals reported … See more In total, 33 distinct variants in RFX family members (15 RFX3, 4 RFX4, and 14 RFX7) were identified (Table 1). Excluding related individuals, each case involved a novel variant (e.g., there were no recurrent variants). RFX3, … See more WebFive RFX3 Black Motorcycle Gloves - New! Fast Shipping! Condition: New with tags Size Quantity: 2 available Price: AU $112.14 List price AU $224.87 Save AU $112.73 (50% … atlas yarn