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Phospho-sting-s366

WebOct 19, 2024 · Here, we looked for a mechanism that explains how STING-dependent immune signalling is ended. We tracked activated STING (phosphorylated at S366; hereafter pSTING)) (ref. 17) along its intracellular trafficking route by high-resolution confocal and Airyscan microscopy in HeLa cells. WebPhospho Sting S366, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 2 PubMed citations. ZERO BIAS - scores, article …

Balancing STING in antimicrobial defense and autoinflammation

WebWestern blot - Phospho-STING-S365 Rabbit pAb (AP1199) Western blot analysis of extracts of THP-1 cells, using Phospho-STING-S365 antibody (AP1199) at 1:1000 dilution.THP-1 cells were treated by PMA (80 nM) at 37℃ for overnight. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. WebOct 19, 2024 · Extended Data Fig. 9 Density maps and structural models of the AP-1–pSTING complex. The density maps (grey mesh) of AP-1 and pSTING contoured at 3σ. The protein structures fitted into the density... pensford swap pricing https://smallvilletravel.com

(19781) Phospho-STING (Ser366) (D7C3S) Rabbit mAb

WebPhosphorylated S366 is a docking site for IRF3 and is essential for the subsequent induction of Interferons (IFNs) ( 7, 8 ). Our previous work demonstrated that IRF3 binds to phosphorylated STING in the late endosomal compartment, where TBK1 phosphorylates and activates IRF3 ( 9 ). Additional proteins regulate the trafficking of STING. WebAnti-Phospho-STING-S365 antibody produced in rabbit; find Sigma-Aldrich-SAB5701942 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich ... Anti-Phospho-TMEM173-S366 antibody produced in rabbit. View Price and Availability. ... Anti-phospho-Smad2/3 (pThr 8) antibody produced in rabbit. affinity ... WebFeb 15, 2024 · Here, we investigated the relationship between cGAS and phospho-STING (S366) protein expression levels in treatment-naïve LUAD tumors from the MD Anderson Cancer Center (MDACC) PROSPECT trial (n=120). As expected, phospho-STING (S366) protein levels were significantly correlated with cGAS protein levels (p=0.010) (Figure 1A). pensford way frome

Phosphorylation of innate immune adaptor proteins …

Category:Phospho-STING/TMEM173-S366 Rabbit pAb (AP1223)

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Phospho-sting-s366

Phosphorylation of innate immune adaptor proteins …

WebPhospho-STING (Ser366) (E9A9K) Rabbit mAb from Cell Signaling Technology Supplier PageView Company Product Page Product Specs Company Info Reviews Back To Top … WebJan 29, 2015 · STING S366 phosphorylation after HT-DNA transfection was detected with the p-S366 antibody (fig. S8E). ( E ) S366 phosphorylation of endogenous STING in THP-1 …

Phospho-sting-s366

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WebProduct Description. This Cell Signaling Technology antibody is conjugated to Alexa Fluor ® 488 fluorescent dye and tested in-house for direct flow cytometric and immunofluorescent analysis in human cells. The antibody is expected to exhibit the same species cross-reactivity as the unconjugated Phospho-STING (Ser366) (D8K6H) Rabbit mAb #40818. WebPhospho-TMEM173/STING (Ser366) Antibody Phospho-TMEM173/STING (Ser366) Antibody - #AF7416 (6) (9) WB IHC IF/ICC pElisa Cites 1 /9 Western blot analysis of extracts from UV treated RAW264. View similar products>> Related products Secondary Antibodies Loading Controls Blocking Peptides Cat.#S0018 Cat.#S0006 Cat.#S0008 Cat.#S0001 Cat.#S0013 …

WebOct 24, 2013 · We conclude that phosphorylation of S366 (S365 in murine STING) occurs after autophagy and may negatively regulate STING activity to prevent sustained type I IFN production following activation by cytosolic dsDNA. Download : Download high-res image (515KB) Download : Download full-size image Figure S2. WebApr 6, 2024 · STING is a transmembrane dimeric protein that is located in the endoplasmic reticulum or in the Golgi apparatus. ... Binding of TBK1 to this motif promotes the …

WebWestern blot - Phospho-STING/TMEM173-S366 Rabbit pAb (AP1223) Western blot analysis of THP-1, using Phospho-STING/TMEM173-S366 … Web靶标信息. STING is a 379 amino acid containing signaling protein that acts as an important component of innate immune signaling. This signaling protein is able to activate both NF …

Web(19781) Phospho-STING (Ser366) (D7C3S) Rabbit mAb Sign in or register to save this reagent to your favourites Supplier Cell Signaling Technology Host Rabbit Type Primary …

Web55. A method of treating, inhibiting, reducing, ameliorating, and/or preventing a cancer and or metastasis in a subject comprising administering to a subject an adoptive immunothe today i will be taught the word of godWebMay 1, 2024 · (A) Heatmap shows correlation of phospho-STING (Ser_366) protein levels with cGAS and other immune-related proteins in the MD Anderson PROSPECT cohort, … today i will be the master of my emotion演讲WebPhospho-STING (Ser366) Antibody (PA5-105674) in ICC/IF. Immunofluorescent analysis of Phospho-STING (Ser366) in HepG2 cells … pens for fashion illustrationPhospho-STING (Ser366) (D7C3S) Rabbit mAb recognizes endogenous levels of STING protein only when phosphorylated at Ser366. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser366 of human STING protein. Background today i will date with yesterday\u0027s youtoday i will date with yesterday\\u0027s youWebHTRF phospho-STING (S366) 64STGPEG HTRF total-STING 64NTGPEG HTRF phospho-TBK1 (S172) 64TBKPEG HTRF total-TBK1 64NTBPEG HTRF phospho-IRF3 (S386) 6FRF3PEG HTRF human IFNb 62HIFNBPEG Compounds References 2’3’ cGAMP C161-Biolog c-diAMP C088-Biolog c-diGMP C057-Biolog DMXAA D5817 –Sigma-Aldrich. pens for ipad air 2WebPhospho-STING (Ser366) (E9A9K) Rabbit mAb recognizes endogenous levels of STING protein only when phosphorylated at Ser366. Species Reactivity: Human Source / Purification Monoclonal antibody is produced … pens for ipad pro