Thr308是什么
WebThe AlphaLISA SureFire Ultra p-AKT1/2/3 (Thr308) assay kit (high volume) is an immunoassay for quantitative detection of phospho-AKT1/2/3 in cellular lysates. We are now two standalone organizations Life Sciences & Diagnostics and Analytical & Enterprise Solutions. Learn More. WebPlasmids construction and DNA mutagenesis. AKT tagged with hemagglutinin (HA) was cloned into the pCI-Neo vector via the XhoI and SalI sites. Mutation of AKT at Thr308 or Ser473 to Alanine were achieved by using the QuickChange II site-directed mutagenesis kit (Stratagene, La Jolla, CA, USA) with the following forward and reversed primers: 5ʹ …
Thr308是什么
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WebMay 16, 2024 · 膜上的PDK1在AKt的Thr308位点将其磷酸化,导致Akt的部分激活。 Ser473位点被mTORC2磷酸化,可激发Akt的完全的酶活性。 在选择位点的时候,可以从 … Web核磁共振波谱法(英语:Nuclear Magnetic Resonance spectroscopy,简称 NMR spectroscopy 或 NMRS ),又称核磁共振波谱,是将核磁共振现象应用于测定分子结构的 …
Web1、akt:胰岛素等生长和存活因子都可以激活Akt信号途径。Akt的Thr308可以被PDK1磷酸化。 2、akt1:研究人员已经在人类乳腺癌、结肠直肠癌和卵巢癌中发现了AKT1中的一个突变,该突变通过增强其膜联系作用来激发这种激酶,从而将AKT1与癌症的发生直接关联了起来 … WebETH以不同方式对不同的人都具有宝贵的价值。. 对于Ethereum用户来说,ETH很有价值,因为它让您支付交易费用。. 另一些人认为它是一种价值的数字存储,因为新的ETH的创建 …
WebMonoclonal Antibody for studying Akt2 (Thr309) phosphate/Akt3 (Thr305) phosphate/Akt1 (Thr308) phosphate. Cited in 872 publications. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, Phospho-Akt (Thr308) (C31E5E) Rabbit Monoclonal Antibody (CST #2965) is ready to ship. WebMay 31, 2024 · 如果是做细胞凋亡、细胞周期、细胞骨架重组、癌症相关的话,Thr308和Ser473两个位点都可能参与其中;如果研究细胞分化,可能需要多关注下Ser473位点; …
WebAug 28, 2024 · Thr308 和 Ser473 分别位于后两个结构域上,PH 和催化结构域在不同的 Akt 异构体中都是相对比较保守的。哺乳动物中 AKT 有 3 种主要的异构体:Akt1,2,3 …
WebJun 23, 2024 · 多层感知机(MLP,Multilayer Perceptron)也叫人工神经网络(ANN,Artificial Neural Network),除了输入输出层,它中间可以有多个隐层,最简单 … memphis liquor and wine 38133http://www.sciben.com/Pc/Product/Details/78b68951-e2dc-4306-b4f1-e2be01cc20a5 memphis list of mayorsWebMar 31, 2024 · Phospho-Akt (Thr308)抗体 对于本抗体,Western检测时一抗要4℃缓慢摇动过夜,如果仅短时间与一抗孵育检测效果较差。 在Western实验后,请注意回收稀释的抗体。 … memphis live musicWebAkt信号通路或者PI3K-Akt信号通路是促进响应胞外信号的信号转导途径。涉及到的核心蛋白是PI3K (磷脂酰肌醇 3-激酶) 和Akt(蛋白激酶B)。一种生长因子的初始刺激引起细胞表面受 … memphis line and twineWebPhospho-AKT1 (Thr308) Antibody (44-602G) in IHC (P) Immunohistochemistry analysis of AKT/PKB (pT308) showing staining in the cytoplasm and nucleus of paraffin-embedded … memphis live traffic camerasWebFig.3. Immunohistochemical analysis of paraffin-embedded mouse lung tissue. 1, Akt (phospho Thr308) 多克隆 Antibody was diluted at 1:200 (4°C, overnight). 2, Sodium citrate … memphis lkWebFlow cytometry of Phospho-Akt1 (Thr308) using C6 cells. Samples were incubated in monoclonal Phospho-Akt1 (Thr308) antibody (Product # MA5-37083) with a dilution of … memphis live news channel